NLST Proves Lives Can Be Saved: Now Comes the Difficult Step of Implementation

December 12, 2010 | Imaging Futures

One of the most extensive and ambitious medical-screening trials in US has been stopped. It’s because of good news: Low-dose helical CT (LDCT) exams can cut lung-cancer deaths by as much as 20%, compared with chest radiography alone, according to early results from the National Lung Screening Trial (NLST).... Read More »

Imaging in Clinical Trials: Endpoints, Biomarkers, and Methods

November 28, 2010 | Priors

This article is the second in a series of three providing a background and primer to radiologists and imaging professionals interested in clinical trials. It offers background on regulatory approval and on the use of surrogate endpoints and imaging biomarkers, as well as touching on the administration of medical... Read More »

Novel Biomarker Rivals SAP in Amyloid Imaging Using SPECT/CT

October 13, 2010 | Image Gallery

The winning entry, left, in a recent vendor-sponsored preclinical- imaging competition presented at the World Molecular Imaging Conference in Kyoto, Japan, compared the amyloid-binding efficacy of the imaging agent 125I- SAP (in use in Europe, but not approved for use in the United States) with a novel peptide tracer devised... Read More »

Keeping Radiology on the Cutting Edge

October 13, 2010 | Clinical Research

Over the past two decades, imaging has undergone revolutionary and evolutionary changes in both the clinical and nonclinical spheres. Part of this evolution has been the acceptance of imaging as an endpoint or marker for evaluation of the efficacy of therapy in clinical trials. As a result, new doors... Read More »

Contract Research Organizations: Radiology’s Newest Revenue Stream

September 10, 2009 | Feature

In the not-too-distant past, the use of imaging as an endpoint in clinical trials was at best considered a novel approach by pharmaceutical and device manufacturers alike. The times, however, are changing, and bringing with them a new revenue stream for the radiology community.

Opening the floodgates... Read More »